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Overexpression of CD47 is associated with brain overgrowth and 16p11.2 deletion syndrome

Copy number variation (CNV) at the 16p11.2 locus is associated with neuropsychiatric disorders, such as autism spectrum disorder and schizophrenia. CNVs of the 16p gene can manifest in opposing head sizes. Carriers of 16p11.2 deletion tend to have macrocephaly (or brain enlargement), while those wit...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Li, Jingling, Brickler, Thomas, Banuelos, Allison, Marjon, Kristopher, Shcherbina, Anna, Banerjee, Sravani, Bian, Jing, Narayanan, Cyndhavi, Weissman, Irving L., Chetty, Sundari
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053942/
https://ncbi.nlm.nih.gov/pubmed/33833053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005483118
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