MAdCAM-1/α4β7 Integrin-Mediated Lymphocyte/Endothelium Interactions Exacerbate Acute Immune-Mediated Hepatitis in Mice

BACKGROUND & AIMS: Aberrant lymphocyte homing could potentially link inflammatory processes in the intestine and the liver, as distinct hepatobiliary diseases frequently develop as extra-intestinal manifestations in inflammatory bowel disease. In this study, we examined the role of the gut-tropi...

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Dettagli Bibliografici
Pubblicato in:Cell Mol Gastroenterol Hepatol
Autori principali: Schippers, Angela, Hübel, Jessica, Heymann, Felix, Clahsen, Thomas, Eswaran, Sreepradha, Schlepütz, Sarah, Püllen, Robin, Gaßler, Nikolaus, Tenbrock, Klaus, Tacke, Frank, Wagner, Norbert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053699/
https://ncbi.nlm.nih.gov/pubmed/33316453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.12.003
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