Pharmacological characterization of PF-00547659, an anti-human MAdCAM monoclonal antibody

BACKGROUND AND PURPOSE: The adhesion molecule mucosal addressin cell adhesion molecule (MAdCAM) plays an essential role in the recruitment of lymphocytes to specialized high endothelial venules of the gastrointestinal tract and in their excessive tissue extravasation observed in inflammatory conditi...

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Detalhes bibliográficos
Main Authors: Pullen, N, Molloy, E, Carter, D, Syntin, P, Clemo, F, Finco-Kent, D, Reagan, W, Zhao, S, Kawabata, T, Sreckovic, S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697799/
https://ncbi.nlm.nih.gov/pubmed/19366349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00137.x
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