Pharmacological characterization of PF-00547659, an anti-human MAdCAM monoclonal antibody

BACKGROUND AND PURPOSE: The adhesion molecule mucosal addressin cell adhesion molecule (MAdCAM) plays an essential role in the recruitment of lymphocytes to specialized high endothelial venules of the gastrointestinal tract and in their excessive tissue extravasation observed in inflammatory conditi...

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Главные авторы: Pullen, N, Molloy, E, Carter, D, Syntin, P, Clemo, F, Finco-Kent, D, Reagan, W, Zhao, S, Kawabata, T, Sreckovic, S
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2009
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Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697799/
https://ncbi.nlm.nih.gov/pubmed/19366349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00137.x
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