IL-15 superagonist N-803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34(+) progenitor-derived NK cells

Allogeneic natural killer (NK) cell transfer is a potential immunotherapy to eliminate and control cancer. A promising source are CD34 + hematopoietic progenitor cells (HPCs), since large numbers of cytotoxic NK cells can be generated. Effective boosting of NK cell function can be achieved by interl...

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書誌詳細
出版年:Cancer Immunol Immunother
主要な著者: Van der Meer, J. M. R., Maas, R. J. A., Guldevall, K., Klarenaar, K., de Jonge, P. K. J. D., Evert, J. S. Hoogstad-van, van der Waart, A. B., Cany, J., Safrit, J. T., Lee, J. H., Wagena, E., Friedl, P., Önfelt, B., Massuger, L. F., Schaap, N. P. M., Jansen, J. H., Hobo, W., Dolstra, H.
フォーマット: Artigo
言語:Inglês
出版事項: Springer Berlin Heidelberg 2020
主題:
Original Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053152/
https://ncbi.nlm.nih.gov/pubmed/33140189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02749-8
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