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Ultraviolet-induced RNA:DNA hybrids interfere with chromosomal DNA synthesis
Ultraviolet (UV) induces pyrimidine dimers (PDs) in DNA and replication-dependent fragmentation in chromosomes. The rnhAB mutants in Escherichia coli, accumulating R-loops and single DNA-rNs, are generally resistant to DNA damage, but are surprisingly UV-sensitive, even though they remove PDs normal...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8053090/ https://ncbi.nlm.nih.gov/pubmed/33693789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab147 |
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