Germline variation in the insulin-like growth factor pathway and risk of Barrett’s esophagus and esophageal adenocarcinoma

Genome-wide association studies (GWAS) of esophageal adenocarcinoma (EAC) and its precursor, Barrett’s esophagus (BE), have uncovered significant genetic components of risk, but most heritability remains unexplained. Targeted assessment of genetic variation in biologically relevant pathways using no...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Dighe, Shruti G, Chen, Jianhong, Yan, Li, He, Qianchuan, Gharahkhani, Puya, Onstad, Lynn, Levine, David M, Palles, Claire, Ye, Weimin, Gammon, Marilie D, Iyer, Prasad G, Anderson, Lesley A, Liu, Geoffrey, Wu, Anna H, Dai, James Y, Chow, Wong-Ho, Risch, Harvey A, Lagergren, Jesper, Shaheen, Nicholas J, Bernstein, Leslie, Corley, Douglas A, Prenen, Hans, deCaestecker, John, MacDonald, David, Moayyedi, Paul, Barr, Hugh, Love, Sharon B, Chegwidden, Laura, Attwood, Stephen, Watson, Peter, Harrison, Rebecca, Ott, Katja, Moebus, Susanne, Venerito, Marino, Lang, Hauke, Mayershofer, Rupert, Knapp, Michael, Veits, Lothar, Gerges, Christian, Weismüller, Josef, Gockel, Ines, Vashist, Yogesh, Nöthen, Markus M, Izbicki, Jakob R, Manner, Hendrik, Neuhaus, Horst, Rösch, Thomas, Böhmer, Anne C, Hölscher, Arnulf H, Anders, Mario, Pech, Oliver, Schumacher, Brigitte, Schmidt, Claudia, Schmidt, Thomas, Noder, Tania, Lorenz, Dietmar, Vieth, Michael, May, Andrea, Hess, Timo, Kreuser, Nicole, Becker, Jessica, Ell, Christian, Ambrosone, Christine B, Moysich, Kirsten B, MacGregor, Stuart, Tomlinson, Ian, Whiteman, David C, Jankowski, Janusz, Schumacher, Johannes, Vaughan, Thomas L, Madeleine, Margaret M, Hardie, Laura J, Buas, Matthew F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Cancer Biomarkers and Molecular Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052954/
https://ncbi.nlm.nih.gov/pubmed/33300568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgaa132
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