Chronic gastroesophageal reflux disease shares genetic background with esophageal adenocarcinoma and Barrett's esophagus

Esophageal adenocarcinoma (EA) is a rapidly fatal cancer with rising incidence in the developed world. Most EAs arise in a metaplastic epithelium, Barrett's esophagus (BE), which is associated with greatly increased risk of EA. One of the key risk factors for both BE and EA is chronic gastroeso...

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Bibliografiska uppgifter
I publikationen:Hum Mol Genet
Huvudupphovsmän: Gharahkhani, Puya, Tung, Joyce, Hinds, David, Mishra, Aniket, Vaughan, Thomas L., Whiteman, David C., MacGregor, Stuart
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2016
Ämnen:
Association Studies Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743691/
https://ncbi.nlm.nih.gov/pubmed/26704365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv512
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