Germline Genetic Contributions to Risk for Esophageal Adenocarcinoma, Barrett’s Esophagus, and Gastroesophageal Reflux

BACKGROUND: Esophageal adenocarcinoma (EA) is an increasingly common cancer with poor survival. Barrett’s esophagus (BE) is the main precursor to EA, and every year 0.12% to 0.5% of BE patients progress to EA. BE typically arises on a background of chronic gastroesophageal reflux (GERD), one of the...

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Hauptverfasser: Ek, Weronica E., Levine, David M., D’Amato, Mauro, Pedersen, Nancy L., Magnusson, Patrik K. E., Bresso, Francesca, Onstad, Lynn E., Schmidt, Peter T., Törnblom, Hans, Nordenstedt, Helena, Romero, Yvonne, Chow, Wong-Ho, Murray, Liam J., Gammon, Marilie D., Liu, Geoffrey, Bernstein, Leslie, Casson, Alan G., Risch, Harvey A., Shaheen, Nicholas J., Bird, Nigel C., Reid, Brian J., Corley, Douglas A., Hardie, Laura J., Ye, Weimin, Wu, Anna H., Zucchelli, Marco, Spector, Tim D., Hysi, Pirro, Vaughan, Thomas L., Whiteman, David C., MacGregor, Stuart
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833931/
https://ncbi.nlm.nih.gov/pubmed/24168968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt303
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