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Germline variation in the insulin-like growth factor pathway and risk of Barrett’s esophagus and esophageal adenocarcinoma

Genome-wide association studies (GWAS) of esophageal adenocarcinoma (EAC) and its precursor, Barrett’s esophagus (BE), have uncovered significant genetic components of risk, but most heritability remains unexplained. Targeted assessment of genetic variation in biologically relevant pathways using no...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Carcinogenesis
Prif Awduron: Dighe, Shruti G, Chen, Jianhong, Yan, Li, He, Qianchuan, Gharahkhani, Puya, Onstad, Lynn, Levine, David M, Palles, Claire, Ye, Weimin, Gammon, Marilie D, Iyer, Prasad G, Anderson, Lesley A, Liu, Geoffrey, Wu, Anna H, Dai, James Y, Chow, Wong-Ho, Risch, Harvey A, Lagergren, Jesper, Shaheen, Nicholas J, Bernstein, Leslie, Corley, Douglas A, Prenen, Hans, deCaestecker, John, MacDonald, David, Moayyedi, Paul, Barr, Hugh, Love, Sharon B, Chegwidden, Laura, Attwood, Stephen, Watson, Peter, Harrison, Rebecca, Ott, Katja, Moebus, Susanne, Venerito, Marino, Lang, Hauke, Mayershofer, Rupert, Knapp, Michael, Veits, Lothar, Gerges, Christian, Weismüller, Josef, Gockel, Ines, Vashist, Yogesh, Nöthen, Markus M, Izbicki, Jakob R, Manner, Hendrik, Neuhaus, Horst, Rösch, Thomas, Böhmer, Anne C, Hölscher, Arnulf H, Anders, Mario, Pech, Oliver, Schumacher, Brigitte, Schmidt, Claudia, Schmidt, Thomas, Noder, Tania, Lorenz, Dietmar, Vieth, Michael, May, Andrea, Hess, Timo, Kreuser, Nicole, Becker, Jessica, Ell, Christian, Ambrosone, Christine B, Moysich, Kirsten B, MacGregor, Stuart, Tomlinson, Ian, Whiteman, David C, Jankowski, Janusz, Schumacher, Johannes, Vaughan, Thomas L, Madeleine, Margaret M, Hardie, Laura J, Buas, Matthew F
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052954/
https://ncbi.nlm.nih.gov/pubmed/33300568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgaa132
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