Molecular characterisation of titin N2A and its binding of CARP reveals a titin/actin cross-linking mechanism

Striated muscle responds to mechanical overload by rapidly up-regulating the expression of the cardiac ankyrin repeat protein, CARP, which then targets the sarcomere by binding to titin N2A in the I-band region. To date, the role of this interaction in the stress response of muscle remains poorly un...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Zhou, Tiankun, Fleming, Jennifer R., Lange, Stephan, Hessel, Anthony L., Bogomolovas, Julius, Stronczek, Chiara, Grundei, David, Ghassemian, Majid, Biju, Andrea, Börgeson, Emma, Bullard, Belinda, Linke, Wolfgang A, Chen, Ju, Kovermann, Michael, Mayans, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052292/
https://ncbi.nlm.nih.gov/pubmed/33647290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2021.166901
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados