The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation

While the mechanisms by which chemical signals control cell fate have been well studied, the impact of mechanical inputs on cell fate decisions is not well understood. Here, using the well-defined system of keratinocyte differentiation in the skin, we examine whether and how direct force transmissio...

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Publicat a:eLife
Autors principals: Carley, Emma, Stewart, Rachel M, Zieman, Abigail, Jalilian, Iman, King, Diane E, Zubek, Amanda, Lin, Samantha, Horsley, Valerie, King, Megan C
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2021
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051949/
https://ncbi.nlm.nih.gov/pubmed/33779546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58541
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