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The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation

While the mechanisms by which chemical signals control cell fate have been well studied, the impact of mechanical inputs on cell fate decisions is not well understood. Here, using the well-defined system of keratinocyte differentiation in the skin, we examine whether and how direct force transmissio...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Carley, Emma, Stewart, Rachel M, Zieman, Abigail, Jalilian, Iman, King, Diane E, Zubek, Amanda, Lin, Samantha, Horsley, Valerie, King, Megan C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051949/
https://ncbi.nlm.nih.gov/pubmed/33779546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58541
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