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Imaging integrin tension and cellular force at submicron resolution with integrative tension sensor

Molecular tension transmitted by integrin-ligand bonds is the fundamental mechanical signal in the integrin pathway that plays significant roles in many cell functions and behaviors. To calibrate and image integrin tension with high force sensitivity and spatial resolution, we developed ITS, a DNA-b...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Zhao, Yuanchang, Wetter, Nathaniel M, Wang, Xuefeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613363/
https://ncbi.nlm.nih.gov/pubmed/31081814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/59476
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