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Molecular Tension Sensors Report Forces Generated by Single Integrin Molecules in Living Cells

Living cells are exquisitely responsive to mechanical cues, yet how cells produce and detect mechanical force remains poorly understood due to a lack of methods that visualize cell-generated forces at the molecular scale. Here we describe Förster resonance energy transfer (FRET)-based molecular tens...

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Detalhes bibliográficos
Main Authors: Morimatsu, Masatoshi, Mekhdjian, Armen H., Adhikari, Arjun S., Dunn, Alexander R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815579/
https://ncbi.nlm.nih.gov/pubmed/23859772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl4005145
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