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Plasticity of ether lipids promotes ferroptosis susceptibility and evasion

Ferroptosis, an iron-dependent, non-apoptotic cell death program, is involved in various degenerative diseases and represents a targetable vulnerability in certain cancers(1). The ferroptosis-susceptible cell state can either preexist in cells arising from certain lineages or be acquired during cell...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Zou, Yilong, Henry, Whitney S., Ricq, Emily L., Graham, Emily T., Phadnis, Vaishnavi V., Maretich, Pema, Paradkar, Sateja, Boehnke, Natalie, Deik, Amy A., Reinhardt, Ferenc, Eaton, John K., Ferguson, Bryan, Wang, Wenyu, Fairman, Joshua, Keys, Heather R., Dančík, Vlado, Clish, Clary B., Clemons, Paul A., Hammond, Paula T., Boyer, Laurie A., Weinberg, Robert A., Schreiber, Stuart L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051864/
https://ncbi.nlm.nih.gov/pubmed/32939090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2732-8
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