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Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis
Ferroptosis is widely involved in degenerative diseases in various tissues including kidney, liver and brain, and is a targetable vulnerability in clear-cell carcinomas and therapy-resistant cancers. Accumulation of phospholipid hydroperoxides in cellular membranes is recognized as the hallmark and...
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| Опубликовано в: : | Nat Chem Biol |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7353921/ https://ncbi.nlm.nih.gov/pubmed/32080622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0472-6 |
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