A carregar...
Blockade of 6-phosphogluconate dehydrogenase generates CD8(+) effector T cells with enhanced anti-tumor function
Although T cell expansion depends on glycolysis, T effector cell differentiation requires signaling via the production of reactive oxygen species (ROS). Because the pentose phosphate pathway (PPP) regulates ROS by generating nicotinamide adenine dinucleotide phosphate (NADPH), we examined how PPP bl...
Na minha lista:
| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8051863/ https://ncbi.nlm.nih.gov/pubmed/33691103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108831 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|