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ChIP-BIT2: a software tool to detect weak binding events using a Bayesian integration approach

BACKGROUND: ChIP-seq combines chromatin immunoprecipitation assays with sequencing and identifies genome-wide binding sites for DNA binding proteins. While many binding sites have strong ChIP-seq ‘peak’ observations and are well captured, there are still regions bound by proteins weakly, with a rela...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Chen, Xi, Shi, Xu, Neuwald, Andrew F., Hilakivi-Clarke, Leena, Clarke, Robert, Xuan, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051094/
https://ncbi.nlm.nih.gov/pubmed/33858322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-04108-5
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