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CRNET: an efficient sampling approach to infer functional regulatory networks by integrating large-scale ChIP-seq and time-course RNA-seq data

MOTIVATION: NGS techniques have been widely applied in genetic and epigenetic studies. Multiple ChIP-seq and RNA-seq profiles can now be jointly used to infer functional regulatory networks (FRNs). However, existing methods suffer from either oversimplified assumption on transcription factor (TF) re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioinformatics
Hauptverfasser: Chen, Xi, Gu, Jinghua, Wang, Xiao, Jung, Jin-Gyoung, Wang, Tian-Li, Hilakivi-Clarke, Leena, Clarke, Robert, Xuan, Jianhua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946876/
https://ncbi.nlm.nih.gov/pubmed/29280996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx827
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