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Fabrication of microneedle patches with lyophilized influenza vaccine suspended in organic solvent

Skin vaccination by microneedle (MN) patch simplifies the immunization process to increase access to vaccines for global health. Lyophilization has been widely used to stabilize vaccines and other biologics during storage, but is generally not compatible with the MN patch manufacturing processes. In...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Deliv Transl Res
Hauptverfasser: Kim, Yoo Chun, Lee, Jeong Woo, Esser, E. Stein, Kalluri, Haripriya, Joyce, Jessica C., Compans, Richard W., Skountzou, Ioanna, Prausnitz, Mark R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050834/
https://ncbi.nlm.nih.gov/pubmed/33590465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-021-00927-4
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