Stable incorporation of GM-CSF into dissolvable microneedle patch improves skin vaccination against influenza

The widely used influenza subunit vaccine would benefit from increased protection rates in vulnerable populations. Skin immunization by microneedle (MN) patch can increase vaccine immunogenicity, as well as increase vaccination coverage due to simplified administration. To further increase immunogen...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Littauer, Elizabeth Q., Mills, Lisa K., Brock, Nicole, Esser, E. Stein, Romanyuk, Andrey, Pulit-Penaloza, Joanna A., Vassilieva, Elena V., Beaver, Jacob T., Antao, Olivia, Krammer, Florian, Compans, Richard W., Prausnitz, Mark R., Skountzou, Ioanna
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967648/
https://ncbi.nlm.nih.gov/pubmed/29496540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.02.033
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