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Long-term stability of influenza vaccine in a dissolving microneedle patch

This study tested the hypothesis that optimized microneedle patch formulations can stabilize trivalent subunit influenza vaccine during long-term storage outside the cold chain and when exposed to potential stresses found during manufacturing and storage. Formulations containing combinations of treh...

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Bibliographic Details
Published in:Drug Deliv Transl Res
Main Authors: Mistilis, Matthew J., Joyce, Jessica C., Esser, E. Stein, Skountzou, Ioanna, Compans, Richard W., Bommarius, Andreas S., Prausnitz, Mark R.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003766/
https://ncbi.nlm.nih.gov/pubmed/26926241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-016-0282-2
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