Stable incorporation of GM-CSF into dissolvable microneedle patch improves skin vaccination against influenza

The widely used influenza subunit vaccine would benefit from increased protection rates in vulnerable populations. Skin immunization by microneedle (MN) patch can increase vaccine immunogenicity, as well as increase vaccination coverage due to simplified administration. To further increase immunogen...

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Detalles Bibliográficos
Publicado en:J Control Release
Main Authors: Littauer, Elizabeth Q., Mills, Lisa K., Brock, Nicole, Esser, E. Stein, Romanyuk, Andrey, Pulit-Penaloza, Joanna A., Vassilieva, Elena V., Beaver, Jacob T., Antao, Olivia, Krammer, Florian, Compans, Richard W., Prausnitz, Mark R., Skountzou, Ioanna
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967648/
https://ncbi.nlm.nih.gov/pubmed/29496540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.02.033
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