Stable incorporation of GM-CSF into dissolvable microneedle patch improves skin vaccination against influenza

The widely used influenza subunit vaccine would benefit from increased protection rates in vulnerable populations. Skin immunization by microneedle (MN) patch can increase vaccine immunogenicity, as well as increase vaccination coverage due to simplified administration. To further increase immunogen...

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Опубликовано в: :J Control Release
Главные авторы: Littauer, Elizabeth Q., Mills, Lisa K., Brock, Nicole, Esser, E. Stein, Romanyuk, Andrey, Pulit-Penaloza, Joanna A., Vassilieva, Elena V., Beaver, Jacob T., Antao, Olivia, Krammer, Florian, Compans, Richard W., Prausnitz, Mark R., Skountzou, Ioanna
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967648/
https://ncbi.nlm.nih.gov/pubmed/29496540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.02.033
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