Microglial Nox2 Plays a Key Role in the Pathogenesis of Experimental Autoimmune Encephalomyelitis

While oxidative stress has been linked to multiple sclerosis (MS), the role of superoxide-producing phagocyte NADPH oxidase (Nox2) in central nervous system (CNS) pathogenesis remains unclear. This study investigates the impact of Nox2 gene ablation on pro- and anti-inflammatory cytokine and chemoki...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hu, Chih-Fen, Wu, San-Pin, Lin, Gu-Jiun, Shieh, Chi-Chang, Hsu, Chih-Sin, Chen, Jing-Wun, Chen, Shih-Heng, Hong, Jau-Shyong, Chen, Shyi-Jou
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050344/
https://ncbi.nlm.nih.gov/pubmed/33868265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.638381
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