Chimeric CTLA4-CD28-CD3z T Cells Potentiate Antitumor Activity Against CD80/CD86–Positive B Cell Malignancies

The adoptive transfer of chimeric antigen receptor T (CAR T) cells have been recognized as a promising therapeutic strategy for the treatment of hematological malignancies; however, clinical success using CAR T cells for the treatment of solid tumors are still limited since the T-cell function is in...

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Vydáno v:Front Immunol
Hlavní autoři: Lin, Shouheng, Cheng, Lin, Ye, Wei, Li, Shanglin, Zheng, Diwei, Qin, Le, Wu, Qiting, Long, Youguo, Lin, Simiao, Wang, Suna, Huang, Guohua, Li, Peng, Yao, Yao, Sun, Xiaofang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050336/
https://ncbi.nlm.nih.gov/pubmed/33868277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.642528
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