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New phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D(2) receptor regulation and signaling
The dopamine D(2) receptor (D(2)R) is the target of drugs used to treat the symptoms of Parkinson’s disease and schizophrenia. The D(2)R is regulated through its interaction with and phosphorylation by G protein receptor kinases (GRKs) and interaction with arrestins. More recently, D(2)R arrestin-me...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8050214/ https://ncbi.nlm.nih.gov/pubmed/33859231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87417-2 |
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