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Heterologous regulation of agonist-independent μ-opioid receptor phosphorylation by protein kinase C
BACKGROUND AND PURPOSE: Homologous agonist-induced phosphorylation of the μ-opioid receptor (MOR) is initiated at the carboxyl-terminal S375, followed by phosphorylation of T370, T376 and T379. In HEK293 cells, this sequential and hierarchical multi-site phosphorylation is specifically mediated by G...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Publishing Ltd
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3952808/ https://ncbi.nlm.nih.gov/pubmed/24308893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12546 |
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