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Heterologous regulation of agonist-independent μ-opioid receptor phosphorylation by protein kinase C

BACKGROUND AND PURPOSE: Homologous agonist-induced phosphorylation of the μ-opioid receptor (MOR) is initiated at the carboxyl-terminal S375, followed by phosphorylation of T370, T376 and T379. In HEK293 cells, this sequential and hierarchical multi-site phosphorylation is specifically mediated by G...

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Detalhes bibliográficos
Main Authors: Illing, Susann, Mann, Anika, Schulz, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952808/
https://ncbi.nlm.nih.gov/pubmed/24308893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12546
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