miR-33 Silencing Reprograms the Immune Cell Landscape in Atherosclerotic Plaques

RATIONALE: MicroRNA-33 post-transcriptionally represses genes involved in lipid metabolism and energy homeostasis. Targeted inhibition of miR-33 increases plasma HDL cholesterol and promotes atherosclerosis regression, in part, by enhancing reverse cholesterol transport and dampening plaque inflamma...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Afonso, Milessa Silva, Sharma, Monika, Schlegel, Martin, van Solingen, Coen, Koelwyn, Graeme J., Shanley, Lianne C., Beckett, Lauren, Peled, Daniel, Rahman, Karishma, Giannarelli, Chiara, Li, Huilin, Brown, Emily J., Khodadadi-Jamayran, Alireza, Fisher, Edward A., Moore, Kathryn J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049965/
https://ncbi.nlm.nih.gov/pubmed/33593073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.317914
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