Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity

Macrophages accumulate prominently in the visceral adipose tissue (VAT) of obese humans and high fat diet (HFD) fed mice, and this is linked to insulin resistance and type II diabetes. While the mechanisms regulating macrophage recruitment in obesity have been delineated, the signals directing macro...

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Detalhes bibliográficos
Publicado no:Immunometabolism
Main Authors: Sharma, Monika, Schlegel, Martin, Brown, Emily J., Sansbury, Brian E., Weinstock, Ada, Afonso, Milessa S., Corr, Emma M., van Solingen, Coen, Shanley, Lianne C., Peled, Daniel, Ramasamy, Ravichandran, Schmidt, Ann Marie, Spite, Matthew, Fisher, Edward A., Moore, Kathryn J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699780/
https://ncbi.nlm.nih.gov/pubmed/31428465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20900/immunometab20190010
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