Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity

Macrophages accumulate prominently in the visceral adipose tissue (VAT) of obese humans and high fat diet (HFD) fed mice, and this is linked to insulin resistance and type II diabetes. While the mechanisms regulating macrophage recruitment in obesity have been delineated, the signals directing macro...

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Vydáno v:Immunometabolism
Hlavní autoři: Sharma, Monika, Schlegel, Martin, Brown, Emily J., Sansbury, Brian E., Weinstock, Ada, Afonso, Milessa S., Corr, Emma M., van Solingen, Coen, Shanley, Lianne C., Peled, Daniel, Ramasamy, Ravichandran, Schmidt, Ann Marie, Spite, Matthew, Fisher, Edward A., Moore, Kathryn J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699780/
https://ncbi.nlm.nih.gov/pubmed/31428465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20900/immunometab20190010
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