Phosphatidylinositol-3 kinase signaling controls survival and stemness of hematopoietic stem and progenitor cells

Hematopoietic stem and progenitor cells (HSPCs) are multipotent cells giving rise to all blood lineages during life. HSPCs emerge from the ventral wall of the dorsal aorta (VDA) during a specific timespan in embryonic development through endothelial hematopoietic transition (EHT). We investigated th...

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Publicat a:Oncogene
Autors principals: Blokzijl-Franke, Sasja, Ponsioen, Bas, Schulte-Merker, Stefan, Herbomel, Philippe, Kissa, Karima, Choorapoikayil, Suma, den Hertog, Jeroen
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049872/
https://ncbi.nlm.nih.gov/pubmed/33714985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01733-5
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