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Leveraging the cell lineage to predict cell-type specificity of regulatory variation from bulk genomics

Recent computational methods have enabled the inference of the cell-type-specificity of eQTLs based on bulk transcriptomes from highly heterogeneous tissues. However, these methods are limited in their scalability to highly heterogeneous tissues and limited in their broad applicability to any cell-t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genetics
Prif Awduron: Yankovitz, Gal, Cohn, Ofir, Bacharach, Eran, Peshes-Yaloz, Naama, Steuerman, Yael, Iraqi, Fuad A, Gat-Viks, Irit
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049554/
https://ncbi.nlm.nih.gov/pubmed/33734353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/genetics/iyab016
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