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Leveraging the cell lineage to predict cell-type specificity of regulatory variation from bulk genomics

Recent computational methods have enabled the inference of the cell-type-specificity of eQTLs based on bulk transcriptomes from highly heterogeneous tissues. However, these methods are limited in their scalability to highly heterogeneous tissues and limited in their broad applicability to any cell-t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genetics
Hauptverfasser: Yankovitz, Gal, Cohn, Ofir, Bacharach, Eran, Peshes-Yaloz, Naama, Steuerman, Yael, Iraqi, Fuad A, Gat-Viks, Irit
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049554/
https://ncbi.nlm.nih.gov/pubmed/33734353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/genetics/iyab016
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