Cell composition analysis of bulk genomics using single cell data

Single-cell expression profiling (scRNA-seq) is a rich resource of cellular heterogeneity. While profiling every sample under study would be advantageous, it is time-consuming and costly. Here we introduce Cell Population Mapping (CPM), a deconvolution algorithm in which the composition of cell type...

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Pubblicato in:Nat Methods
Autori principali: Frishberg, Amit, Peshes-Yaloz, Naama, Cohn, Ofir, Rosentul, Diana, Steuerman, Yael, Valadarsky, Liran, Yankovitz, Gal, Mandelboim, Michal, Iraqi, Fuad A., Amit, Ido, Mayo, Lior, Bacharach, Eran, Gat-Viks, Irit
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443043/
https://ncbi.nlm.nih.gov/pubmed/30886410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0355-5
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