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CRISPR/Cas9 gene editing for curing sickle cell disease

Sickle cell disease (SCD) is the most common monogenic blood disorder marked by severe pain, end-organ damage, and early mortality. Treatment options for SCD remain very limited. There are only four FDA approved drugs to reduce acute complications. The only curative therapy for SCD is hematopoietic...

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Detalhes bibliográficos
Publicado no:Transfus Apher Sci
Main Authors: Park, So Hyun, Bao, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049447/
https://ncbi.nlm.nih.gov/pubmed/33455878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.transci.2021.103060
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