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FGFR3 overexpression is a useful detection tool for FGFR3 fusions and sequence variations in glioma

BACKGROUND: Fibroblast growth factor receptor (FGFR) inhibitors are currently used in clinical development. A subset of glioblastomas carries gene fusion of FGFR3 and transforming acidic coiled-coil protein 3. The prevalence of other FGFR3 alterations in glioma is currently unclear. METHODS: We perf...

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Detalhes bibliográficos
Publicado no:Neurooncol Pract
Main Authors: Schittenhelm, Jens, Ziegler, Lukas, Sperveslage, Jan, Mittelbronn, Michel, Capper, David, Burghardt, Isabel, Poso, Antti, Biskup, Saskia, Skardelly, Marco, Tabatabai, Ghazaleh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049444/
https://ncbi.nlm.nih.gov/pubmed/33898054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nop/npaa075
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