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ATRX immunostaining predicts IDH and H3F3A status in gliomas

Gliomas are the most frequent intraaxial CNS neoplasms with a heterogeneous molecular background. Recent studies on diffuse gliomas have shown frequent alterations in the genes involved in chromatin remodelling pathways such as α-thalassemia/mental-retardation-syndrome-X-linked gene (ATRX). Yet, the...

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Bibliografske podrobnosti
izdano v:Acta Neuropathol Commun
Main Authors: Ebrahimi, Azadeh, Skardelly, Marco, Bonzheim, Irina, Ott, Ines, Mühleisen, Helmut, Eckert, Franziska, Tabatabai, Ghazaleh, Schittenhelm, Jens
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910252/
https://ncbi.nlm.nih.gov/pubmed/27311324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0331-6
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