The impact of a 1‐hour time interval between pazopanib and subsequent intake of gastric acid suppressants on pazopanib exposure

Co‐treatment with gastric acid suppressants (GAS) in patients taking anticancer drugs that exhibit pH‐dependant absorption may lead to decreased drug exposure and may hamper drug efficacy. In our study, we investigated whether a 1‐hour time interval between subsequent intake of pazopanib and GAS cou...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Int J Cancer
Hlavní autoři: Krens, Stefanie D., Lubberman, Floor J. E., van Egmond, Marthe, Jansman, Frank G. A., Burger, David M., Hamberg, Paul, Vervenne, Walter L., Gelderblom, Hans, van der Graaf, Winette T. A., Desar, Ingrid M. E., van Herpen, Carla M. L., van Erp, Nielka P.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2021
Témata:
Cancer Therapy and Prevention
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048885/
https://ncbi.nlm.nih.gov/pubmed/33428771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.33469
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky