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The impact of a 1‐hour time interval between pazopanib and subsequent intake of gastric acid suppressants on pazopanib exposure

Co‐treatment with gastric acid suppressants (GAS) in patients taking anticancer drugs that exhibit pH‐dependant absorption may lead to decreased drug exposure and may hamper drug efficacy. In our study, we investigated whether a 1‐hour time interval between subsequent intake of pazopanib and GAS cou...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Krens, Stefanie D., Lubberman, Floor J. E., van Egmond, Marthe, Jansman, Frank G. A., Burger, David M., Hamberg, Paul, Vervenne, Walter L., Gelderblom, Hans, van der Graaf, Winette T. A., Desar, Ingrid M. E., van Herpen, Carla M. L., van Erp, Nielka P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048885/
https://ncbi.nlm.nih.gov/pubmed/33428771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.33469
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