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Abnormal synaptic pruning during adolescence underlying the development of psychotic disorders

PURPOSE OF REVIEW: Excessive synaptic pruning has first been suggested by Irwin Feinberg (1982) as an important pillar in the pathophysiology in schizophrenia (SCZ). This article reviews recent developments highlighting factors implicated in aberrant synaptic pruning and its contribution to disease...

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Vydáno v:Curr Opin Psychiatry
Hlavní autoři: Germann, Monique, Brederoo, Sanne G., Sommer, Iris E.C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048735/
https://ncbi.nlm.nih.gov/pubmed/33560023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/YCO.0000000000000696
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