Abnormal synaptic pruning during adolescence underlying the development of psychotic disorders

PURPOSE OF REVIEW: Excessive synaptic pruning has first been suggested by Irwin Feinberg (1982) as an important pillar in the pathophysiology in schizophrenia (SCZ). This article reviews recent developments highlighting factors implicated in aberrant synaptic pruning and its contribution to disease...

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Publicat a:Curr Opin Psychiatry
Autors principals: Germann, Monique, Brederoo, Sanne G., Sommer, Iris E.C.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2021
Matèries:
SCHIZOPHRENIA AND RELATED DISORDERS: Edited by Lynn E. DeLisi and Iris E.C. Sommer
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048735/
https://ncbi.nlm.nih.gov/pubmed/33560023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/YCO.0000000000000696
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