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Abnormal synaptic pruning during adolescence underlying the development of psychotic disorders

PURPOSE OF REVIEW: Excessive synaptic pruning has first been suggested by Irwin Feinberg (1982) as an important pillar in the pathophysiology in schizophrenia (SCZ). This article reviews recent developments highlighting factors implicated in aberrant synaptic pruning and its contribution to disease...

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Publicado en:Curr Opin Psychiatry
Autores principales: Germann, Monique, Brederoo, Sanne G., Sommer, Iris E.C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048735/
https://ncbi.nlm.nih.gov/pubmed/33560023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/YCO.0000000000000696
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