Abnormal synaptic pruning during adolescence underlying the development of psychotic disorders

PURPOSE OF REVIEW: Excessive synaptic pruning has first been suggested by Irwin Feinberg (1982) as an important pillar in the pathophysiology in schizophrenia (SCZ). This article reviews recent developments highlighting factors implicated in aberrant synaptic pruning and its contribution to disease...

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Опубликовано в: :Curr Opin Psychiatry
Главные авторы: Germann, Monique, Brederoo, Sanne G., Sommer, Iris E.C.
Формат: Artigo
Язык:Inglês
Опубликовано: Lippincott Williams & Wilkins 2021
Предметы:
SCHIZOPHRENIA AND RELATED DISORDERS: Edited by Lynn E. DeLisi and Iris E.C. Sommer
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048735/
https://ncbi.nlm.nih.gov/pubmed/33560023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/YCO.0000000000000696
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