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Brain Microglial Activation Increased in Glucocerebrosidase (GBA) Mutation Carriers without Parkinson's disease

BACKGROUND: Glucocerebrosidase gene mutations are a common genetic risk factor for Parkinson's disease. They exhibit incomplete penetrance. The objective of the present study was to measure microglial activation and dopamine integrity in glucocerebrosidase gene mutation carriers without Parkins...

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Detalhes bibliográficos
Publicado no:Mov Disord
Main Authors: Mullin, Stephen, Stokholm, Morten Gersel, Hughes, Derralyn, Mehta, Atul, Parbo, Peter, Hinz, Rainer, Pavese, Nicola, Brooks, David J., Schapira, Anthony H.V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048428/
https://ncbi.nlm.nih.gov/pubmed/33278043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.28375
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