Evolution and clustering of prodromal parkinsonian features in GBA1 carriers

BACKGROUND: Five to 25% of patients with PD carry glucocerebrosidase gene mutations, and 10% to 30% of glucocerebrosidase carriers will develop PD by age 80. Stratification of PD risk in glucocerebrosidase carriers provides an opportunity to target disease‐modifying therapies. OBJECTIVE: Cross‐secti...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mov Disord
Autori principali: Mullin, Stephen, Beavan, Michelle, Bestwick, Jonathan, McNeill, Alisdair, Proukakis, Christos, Cox, Timothy, Hughes, Derralynn, Mehta, Atul, Zetterberg, Henrik, Schapira, Anthony H.V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2019
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790937/
https://ncbi.nlm.nih.gov/pubmed/31251436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.27775
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