Do gabapentin or pregabalin directly modulate the µ receptor?

BACKGROUND: Pregabalin and gabapentin improve neuropathic pain symptoms but there are emerging concerns regarding their misuse. This is more pronounced among patients with substance use disorder, particularly involving opioids. Co-ingestion of gabapentinoids with opioids is increasingly identified i...

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Bibliographic Details
Published in:PeerJ
Main Authors: Manandhar, Preeti, Murnion, Bridin Patricia, Grimsey, Natasha L., Connor, Mark, Santiago, Marina
Format: Artigo
Language:Inglês
Published: PeerJ Inc. 2021
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048397/
https://ncbi.nlm.nih.gov/pubmed/33954038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.11175
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