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Palladium–Protein Oxidative Addition Complexes by Amine-Selective Acylation

Palladium oxidative addition complexes (OACs) are traditionally accessed by treating an aryl halide-containing substrate with a palladium(0) source. Here, a new strategy to selectively prepare stable OACs from amino groups on native proteins is presented. The approach relies on an amine-selective ac...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Dhanjee, Heemal H., Buslov, Ivan, Windsor, Ian W., Raines, Ronald T., Pentelute, Bradley L., Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048385/
https://ncbi.nlm.nih.gov/pubmed/33319995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c09180
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