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In vitro culture, drug sensitivity, and transcriptome of Plasmodium vivax hypnozoites

The unique relapsing nature of Plasmodium vivax infection is a major barrier to malaria eradication. Upon infection, dormant liver stage forms, hypnozoites, linger for weeks to months and then relapse to cause recurrent blood stage infection. Very little is known about hypnozoite biology; definitive...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Gural, Nil, Mancio-Silva, Liliana, Miller, Alex B., Galstian, Ani, Butty, Vincent L., Levine, Stuart S., Patrapuvich, Rapatbhorn, Desai, Salil P., Mikolajczak, Sebastian A., Kappe, Stefan H.I., Fleming, Heather E., March, Sandra, Sattabongkot, Jetsumon, Bhatia, Sangeeta N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048090/
https://ncbi.nlm.nih.gov/pubmed/29478773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.01.002
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