Plasmodium vivax liver stage development and hypnozoite persistence in human liver-chimeric mice

Plasmodium vivax malaria is characterized by periodic relapses of symptomatic blood stage parasite infections likely initiated by activation of dormant liver stage parasites -hypnozoites. The lack of tractable animal models for P. vivax constitutes a severe obstacle to investigate this unique aspect...

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Udgivet i:Cell Host Microbe
Main Authors: Mikolajczak, Sebastian A., Vaughan, Ashley M., Kangwanrangsan, Niwat, Roobsoong, Wanlapa, Fishbaugher, Matthew, Yimamnuaychok, Narathatai, Rezakhani, Nastaran, Lakshmanan, Viswanathan, Singh, Naresh, Kaushansky, Alexis, Camargo, Nelly, Baldwin, Michael, Lindner, Scott E., Adams, John H., Prachumsri, Jetsumon, Kappe, Stefan H.I.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299596/
https://ncbi.nlm.nih.gov/pubmed/25800544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.02.011
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