Single-cell RNA-seq reveals dynamic change in tumor microenvironment during pancreatic ductal adenocarcinoma malignant progression

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is most aggressive among all gastrointestinal tumors. The complex intra-tumor heterogeneity and special tumor microenvironment in PDAC bring great challenges for developing effective treatment strategies. We aimed to delineate dynamic changes of tu...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Chen, Kai, Wang, Qi, Li, Mingzhe, Guo, Huahu, Liu, Weikang, Wang, Feng, Tian, Xiaodong, Yang, Yinmo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047497/
https://ncbi.nlm.nih.gov/pubmed/33819739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103315
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